Myambutol
This medication is indicated to support treatment of tuberculosis and developed to address mycobacterial infection in combination therapy.
Strengths: 200 · 400 · 600 · 800mg
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Medicine details
- Conditions
- Therapeutic class
Antitubercular Agent
- Pharmacological class
Ethambutol
- Contraindications
hypersensitivity to ethambutol; pre-existing optic neuritis
- Precautions and warnings
regular eye examinations required; caution in renal impairment
- Minor side effects
nausea; headache; dizziness
- Moderate side effects
hyperuricaemia
- Serious side effects
optic neuritis — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Lederle
- Onset Time
not applicable
- Duration
6–12 months
- Storage instructions
Store at controlled room temperature.
- Drug interactions
Aluminium hydroxide
- Age restrictions
Not recommended for children unable to perform vision tests.
Patient summary
This medication is indicated to support treatment of tuberculosis and developed to address mycobacterial infection in combination therapy.
Mechanism of action
Ethambutol inhibits the synthesis of the mycobacterial cell wall by interfering with the incorporation of mycolic acids, specifically acting on the arabinosyl transferase enzyme causing cell death.
Pregnancy and breastfeeding
Pregnancy: safe to use if necessary for TB treatment. Breastfeeding: small amounts are excreted, but generally considered safe.
Myambutol
This medication is indicated to support treatment of tuberculosis and developed to address mycobacterial infection in combination therapy.
Editorial Notes
- Active ingredient(s): Ethambutol
- Listed indication(s): Tuberculosis
Usually available as
- 360 tablets - 400 mg97-400-mg-3638
- 180 tablets - 600 mg97-600-mg-3643
- 180 tablets - 800 mg97-800-mg-3650