Minipress

This medicine is indicated for hypertension and designed to mitigate high blood pressure through peripheral vascular dilation.

Strengths: 1 · 2mg

Medicine details

Conditions
Therapeutic class

Alpha Adrenoceptor Antagonist

Pharmacological class

Alpha-1 Blocker

Known off-label uses

benign prostatic hyperplasia

Contraindications

hypersensitivity to quinazolines

Precautions and warnings

risk of orthostatic hypotension with first dose; do not drive after first dose

Minor side effects

dizziness; headache; drowsiness; nausea

Moderate side effects

palpitations; orthostatic hypotension

Serious side effects

syncope — requires immediate medical attention

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

1–2 hours

Duration

6–10 hours

Storage instructions

Store at room temperature away from light.

Drug interactions

Other antihypertensives; Alcohol

Age restrictions

Use with caution.

Pregnancy and breastfeeding

Pregnancy: use only if necessary. Breastfeeding: exercise caution.

Patient summary

This medicine is indicated for hypertension and designed to mitigate high blood pressure through peripheral vascular dilation.

Mechanism of action

Prazosin is a competitive antagonist of alpha-1 adrenergic receptors. It causes peripheral vasodilation by preventing the action of norepinephrine on smooth muscles in blood vessels, which reduces total peripheral resistance.

Minipress

This medicine is indicated for hypertension and designed to mitigate high blood pressure through peripheral vascular dilation.

Editorial Notes

  • Active ingredient(s): Prazosin
  • Listed indication(s): Hypertension

Usually available as

  • 180 tablets - 1 mg101-1-mg-3548
  • 180 tablets - 2 mg101-2-mg-3555