Lioresal
Designed to relieve muscle spasms to support motor function.
Strengths: 10 · 25mg
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Medicine details
- Therapeutic class
Muscle Relaxant
- Pharmacological class
GABA-B Agonist
- Known off-label uses
hiccups; alcohol withdrawal
- Contraindications
hypersensitivity to baclofen; porphyria; peptic ulcer
- Precautions and warnings
do not stop treatment abruptly; may impair ability to drive or operate machinery
- Minor side effects
somnolence; fatigue; dizziness; nausea
- Moderate side effects
muscle weakness; confusional state; headache; constipation
- Dosage forms
Tablet; Oral solution
- Administration route
Oral use
- Patient summary
Designed to relieve muscle spasms to support motor function.
- Prescription status
POM
- Manufacturer
Novartis
- Onset Time
1–2 hours
- Duration
4–8 hours
- Storage instructions
Store below 25°C in a dry place.
- Drug interactions
alcohol; central nervous system depressants; antihypertensives
- Age restrictions
Use with caution in children.
Serious side effects
respiratory depression — requires immediate medical attention; hallucinations — requires immediate medical attention
Mechanism of action
Activates GABA-B receptors in the spinal cord, which inhibits excitatory neurotransmitters to reduce skeletal muscle spasticity.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary. Breastfeeding: Can be used with caution, monitoring the infant.
Lioresal
Designed to relieve muscle spasms to support motor function.
Editorial Notes
- Active ingredient(s): Baclofen
- Listed indication(s): Multiple Sclerosis, Spinal Cord Injury, Spinal Cord Spasm
Usually available as
- 180 tablets - 10 mg202-10-mg-1231
- 60 tablets - 25 mg202-25-mg-3359