Domperidone Tablets

Developed to alleviate digestive discomfort, indicated to support the control of nausea and vomiting.

Strengths: 10mg

Medicine details

Conditions
Alternative names

Motilium

Therapeutic class

Dopamine Antagonist

Pharmacological class

Prokinetic

Contraindications

cardiac conduction disorders; prolactinoma

Precautions and warnings

use lowest effective dose; caution in patients with cardiac history

Minor side effects

dry mouth

Moderate side effects

galactorrhoea; gynaecomastia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Janssen

Onset Time

30–60 minutes

Duration

4–6 hours

Storage instructions

Store below 30°C.

Drug interactions

ketoconazole; erythromycin

Pregnancy and breastfeeding

Pregnancy: Use only if benefit outweighs risk. Breastfeeding: Use with caution.

Serious side effects

cardiac arrhythmia — requires immediate medical attention; sudden cardiac death — requires immediate medical attention

Patient summary

Developed to alleviate digestive discomfort, indicated to support the control of nausea and vomiting.

Mechanism of action

Domperidone is a peripheral dopamine antagonist that increases oesophageal peristalsis, increases lower oesophageal sphincter pressure, and accelerates gastric emptying, preventing gastrointestinal distress.

Domperidone Tablets

Developed to alleviate digestive discomfort, indicated to support the control of nausea and vomiting.

Editorial Notes

  • Active ingredient(s): Domperidone
  • Listed indication(s): Nausea, Vomiting

Available option

  • 360 tablets - 10 mg1185-10-mg-14034