Danocrine
Indicated to manage endometriosis, utilized to support hormonal regulation.
Strengths: 50 · 100 · 200mg
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Medicine details
- Conditions
- Therapeutic class
Androgen
- Pharmacological class
Synthetic Androgen
- Known off-label uses
fibrocystic breast disease
- Precautions and warnings
monitor liver function; monitor for masculinising effects; use contraception
- Minor side effects
weight gain; acne; oily skin
- Moderate side effects
virilisation; menstrual irregularities; hot flushes
- Dosage forms
Capsule, hard
- Administration route
Oral use
- Patient summary
Indicated to manage endometriosis, utilized to support hormonal regulation.
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
4–6 weeks
- Duration
6–12 months
- Storage instructions
Store below 25°C.
- Drug interactions
warfarin; ciclosporin; carbamazepine
- Age restrictions
Not recommended for children.
Contraindications
pregnancy; breastfeeding; androgen-dependent tumours; severe hepatic dysfunction; porphyria
Serious side effects
hepatotoxicity — requires immediate medical attention; thromboembolism — requires immediate medical attention
Mechanism of action
Danazol is a synthetic androgen derived from ethisterone that inhibits the secretion of pituitary gonadotropins, thus suppressing ovarian function and decreasing the production of oestrogen.
Pregnancy and breastfeeding
Pregnancy: Contraindicated; must use reliable contraception. Breastfeeding: Contraindicated.
Danocrine
Indicated to manage endometriosis, utilized to support hormonal regulation.
Editorial Notes
- Active ingredient(s): Danazol
- Listed indication(s): Endometriosis, Hereditary Angioedema
Usually available as
- 90 tablets - 50 mg730-50-mg-1003
- 60 tablets - 100 mg730-100-mg-993
- 30 tablets - 200 mg730-200-mg-997