Zyvox

This antibiotic is indicated for serious bacterial infections developed to target resistant organisms and support recovery during acute illness.

Strengths: 600mg

Medicine details

Therapeutic class

Oxazolidinone Antibiotic

Pharmacological class

Oxazolidinone

Contraindications

hypersensitivity to linezolid; uncontrolled hypertension

Minor side effects

diarrhoea; nausea; headache

Moderate side effects

oral candidiasis; peripheral neuropathy; anaemia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

1–2 hours

Duration

12 hours

Storage instructions

Store at room temperature, protected from moisture and light.

Drug interactions

Pseudoephedrine; SSRIs; MAO inhibitors

Age restrictions

Use with caution in paediatric patients.

Precautions and warnings

regular blood monitoring recommended; avoid excessive intake of tyramine-rich foods

Serious side effects

severe blood dyscrasias — requires immediate medical attention; serotonin syndrome — requires immediate medical attention

Patient summary

This antibiotic is indicated for serious bacterial infections developed to target resistant organisms and support recovery during acute illness.

Mechanism of action

Linezolid inhibits bacterial protein synthesis by binding to a site on the bacterial 23S ribosomal RNA of the 50S subunit, preventing the formation of the functional 70S initiation complex.

Pregnancy and breastfeeding

Pregnancy: Not recommended unless clearly indicated. Breastfeeding: Discontinue breastfeeding during treatment.

Zyvox

This antibiotic is indicated for serious bacterial infections developed to target resistant organisms and support recovery during acute illness.

Editorial Notes

  • Active ingredient(s): Linezolid
  • Listed indication(s): Pneumonia, Skin and Soft Tissue Infection

Available option

  • 12 tablets - 600 mg440-600-mg-1698