Namenda

Intended to target cognitive decline in Alzheimer's disease, this medication is designed to support mental function and alleviate symptoms of moderate to severe dementia.

Strengths: 5 · 10mg

Medicine details

Alternative names

Ebixa

Therapeutic class

NMDA Receptor Antagonist

Pharmacological class

Adamantane Derivative

Contraindications

hypersensitivity to memantine

Precautions and warnings

use with caution in renal impairment; monitor patients with epilepsy

Minor side effects

dizziness; headache; constipation; somnolence

Moderate side effects

hypertension; confusion; gait disturbance

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Merz Pharmaceuticals

Onset Time

2–4 weeks

Duration

Indefinite therapy

Storage instructions

Store in a cool, dry place.

Drug interactions

amantadine; ketamine; dextromethorphan

Age restrictions

Not for paediatric use.

Serious side effects

psychosis — requires immediate medical attention; seizures — requires immediate medical attention

Patient summary

Intended to target cognitive decline in Alzheimer's disease, this medication is designed to support mental function and alleviate symptoms of moderate to severe dementia.

Mechanism of action

Memantine acts as an uncompetitive antagonist of NMDA receptors in the central nervous system. It mitigates the effects of pathologically elevated glutamate levels which can contribute to neurodegeneration.

Pregnancy and breastfeeding

Pregnancy: Not recommended if benefit does not outweigh risk. Breastfeeding: Not recommended.

Namenda

Intended to target cognitive decline in Alzheimer’s disease, this medication is designed to support mental function and alleviate symptoms of moderate to severe dementia.

Editorial Notes

  • Active ingredient(s): Memantine
  • Listed indication(s): Alzheimer’s Disease

Usually available as

  • 180 tablets - 5 mg140-5-mg-15566
  • 180 tablets - 10 mg140-10-mg-15562