Lamprene
The treatment is indicated to alleviate leprosy symptoms and is utilized to support long-term management of mycobacterial infections.
Strengths: 50mg
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Medicine details
- Conditions
- Therapeutic class
Antimycobacterial
- Pharmacological class
Phenazine derivative
- Contraindications
hypersensitivity to clofazimine; severe hepatic impairment
- Precautions and warnings
may cause skin discoloration; monitor for gastrointestinal issues
- Minor side effects
skin pigmentation; dry skin; nausea
- Moderate side effects
abdominal ache; diarrhoea
- Dosage forms
Capsule, soft
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Novartis
- Onset Time
weeks
- Duration
months
- Storage instructions
Store in a cool, dry place.
- Drug interactions
bedaquiline
- Age restrictions
Consult specialist for dosage.
- Pregnancy and breastfeeding
Pregnancy: Use only if necessary. Breastfeeding: Transfer to breast milk occurs.
Serious side effects
splenic infarction — requires immediate medical attention; bowel obstruction — requires immediate medical attention
Patient summary
The treatment is indicated to alleviate leprosy symptoms and is utilized to support long-term management of mycobacterial infections.
Mechanism of action
Clofazimine is a non-bactericidal agent that binds to mycobacterial DNA, inhibiting mycobacterial growth. it also exerts anti-inflammatory effects, which helps mitigate the immune response and discolouration effects in patients.
Lamprene
The treatment is indicated to alleviate leprosy symptoms and is utilized to support long-term management of mycobacterial infections.
Editorial Notes
- Active ingredient(s): Clofazimine
- Listed indication(s): Leprosy
Available option
- 60 tablets - 50 mg642-50-mg-3340