Buspar

Utilized to alleviate symptoms of generalized anxiety, this anxiolytic agent is designed to support mood regulation without significant sedative side effects.

Strengths: 5 · 10mg

Mental Health icon Mental Health Buspirone icon Buspirone

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Medicine details

Conditions
Therapeutic class

Anxiolytic

Pharmacological class

Azaspirodecanedione

Known off-label uses

major depressive disorder

Minor side effects

dizziness; headache; nausea; lightheadedness

Moderate side effects

insomnia; nervousness; excitement

Serious side effects

serotonin syndrome — requires immediate medical attention

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Bristol-Myers Squibb

Onset Time

1–2 weeks

Duration

4–6 months

Storage instructions

Store below 25°C; keep out of direct light.

Drug interactions

grapefruit; maoi inhibitors; cns depressants

Age restrictions

Not for children under 18 years.

Contraindications

hypersensitivity to buspirone; severe renal impairment; severe hepatic impairment; epilepsy

Precautions and warnings

may impair driving ability; avoid alcohol during treatment; use with caution in elderly patients

Patient summary

Utilized to alleviate symptoms of generalized anxiety, this anxiolytic agent is designed to support mood regulation without significant sedative side effects.

Mechanism of action

Buspirone is a selective serotonin receptor agonist that acts on 5-HT1A receptors. It influences neurotransmitter pathways to help mitigate anxiety without the typical sedative or muscle-relaxant properties of benzodiazepines.

Pregnancy and breastfeeding

Pregnancy: Use only if necessary. Breastfeeding: Caution advised as excretion into milk is unknown.

Buspar

Utilized to alleviate symptoms of generalized anxiety, this anxiolytic agent is designed to support mood regulation without significant sedative side effects.

Editorial Notes

  • Active ingredient(s): Buspirone
  • Listed indication(s): Generalized Anxiety Disorder

Usually available as

  • 270 tablets - 5 mg141-5-mg-2287
  • 120 tablets - 10 mg141-10-mg-2291