Zyban

Designed to support smoking cessation, utilized to relieve nicotine withdrawal and reduce the urge to smoke.

Strengths: 150mg

Medicine details

Alternative names

Wellbutrin

Therapeutic class

Smoking Cessation Aid

Pharmacological class

Aminoketone

Known off-label uses

major depressive disorder

Precautions and warnings

caution in patients with a history of head trauma; may cause dizziness

Minor side effects

insomnia; dry mouth; nausea

Moderate side effects

anxiety; tremor; dizziness; fever

Dosage forms

Prolonged-release tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

GSK

Onset Time

1–2 weeks

Duration

7–9 weeks

Storage instructions

Store at room temperature in a dry place.

Drug interactions

alcohol; MAO inhibitors; citalopram

Age restrictions

Not recommended for those under 18 years.

Pregnancy and breastfeeding

Use only if necessary; consult a physician.

Contraindications

hypersensitivity to bupropion; seizure disorders; eating disorders; concurrent use of MAO inhibitors

Serious side effects

seizures — requires immediate medical attention; anaphylaxis — requires immediate medical attention

Patient summary

Designed to support smoking cessation, utilized to relieve nicotine withdrawal and reduce the urge to smoke.

Mechanism of action

This medicine acts as a non-competitive antagonist of the nicotinic acetylcholine receptor. It also inhibits the neuronal reuptake of norepinephrine and dopamine, though the exact mechanism for assisting smoking cessation is likely related to its noradrenergic and dopaminergic effects.

Zyban

Designed to support smoking cessation, utilized to relieve nicotine withdrawal and reduce the urge to smoke.

Editorial Notes

  • Active ingredient(s): Bupropion
  • Listed indication(s): Smoking Cessation

Available option

  • 90 tablets - 150 mg38-150-mg-4672