Motegrity
Developed to target chronic constipation where laxatives fail, this medication is utilized to support bowel regularity and to alleviate intestinal discomfort.
Strengths: 2mg
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Medicine details
- Conditions
- Alternative names
Resolor
- Therapeutic class
Serotonin (5-HT4) Receptor Agonist
- Pharmacological class
5-HT4 Agonist
- Precautions and warnings
monitor for severe diarrhoea; use caution in cardiac patients
- Minor side effects
headache; nausea; diarrhoea; abdominal pain
- Moderate side effects
dizziness; flatulence; fatigue
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Shire
- Onset Time
1–2 hours
- Duration
24 hours
- Storage instructions
Store in a cool, dry place.
- Drug interactions
atropine; erythromycin
- Age restrictions
Not for use in children under 18.
- Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
hypersensitivity; severe renal impairment; intestinal perforation; severe inflammatory diseases of the intestinal tract
Serious side effects
tachycardia — requires immediate medical attention; palpitations — requires immediate medical attention
Patient summary
Developed to target chronic constipation where laxatives fail, this medication is utilized to support bowel regularity and to alleviate intestinal discomfort.
Mechanism of action
Prucalopride is a high-affinity 5-HT4 receptor agonist that stimulates colonic motility, thereby increasing bowel movement frequency and reducing the symptoms of chronic constipation.
Motegrity
Developed to target chronic constipation where laxatives fail, this medication is utilized to support bowel regularity and to alleviate intestinal discomfort.
Editorial Notes
- Active ingredient(s): Prucalopride
- Listed indication(s): Chronic Constipation
Available option
- 60 tablets - 2 mg1096-2-mg-18212