Sprycel

utilized to target kinase-positive leukaemias and formulated to support the mitigation of malignant cell growth in patients.

Strengths: 50mg

Medicine details

Therapeutic class

Tyrosine Kinase Inhibitor

Pharmacological class

BCR-ABL Kinase Inhibitor

Contraindications

hypersensitivity to dasatinib

Minor side effects

diarrhoea; nausea; headache; fatigue

Moderate side effects

pleural effusion; haemorrhage; anaemia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Bristol-Myers Squibb

Onset Time

variable

Duration

continuous

Storage instructions

Store at room temperature in original packaging.

Drug interactions

proton pump inhibitors; h2 antagonists

Age restrictions

Not recommended for children under 1 year.

Precautions and warnings

monitor for fluid retention; avoid strenuous activity if bleeding occurs; frequent monitoring of full blood count

Serious side effects

severe pulmonary hypertension — requires immediate medical attention; haemorrhage — requires immediate medical attention

Patient summary

utilized to target kinase-positive leukaemias and formulated to support the mitigation of malignant cell growth in patients.

Mechanism of action

Dasatinib is a multi-targeted kinase inhibitor that targets BCR-ABL, SRC family kinases, and other kinases to block the growth of Philadelphia chromosome-positive leukemic cells.

Pregnancy and breastfeeding

Pregnancy: Avoid conception; suspected foetal harm. Breastfeeding: Not recommended.

Sprycel

utilized to target kinase-positive leukaemias and formulated to support the mitigation of malignant cell growth in patients.

Editorial Notes

  • Active ingredient(s): Dasatinib
  • Listed indication(s): Chronic Myeloid Leukaemia, Acute Lymphoblastic Leukaemia

Available option

  • 1 bottle - 50 mg1040-50-mg-13091