Nexletol

Utilized to target hypercholesterolaemia to mitigate cardiovascular risk.

Strengths: 180mg

Medicine details

Alternative names

Nilemdo

Therapeutic class

Adenosine triphosphate-citrate lyase inhibitor

Pharmacological class

Lipid-lowering agent

Contraindications

hypersensitivity to bempedoic acid; pregnancy; breastfeeding

Minor side effects

hyperuricaemia; muscle spasms; back pain; abdominal pain

Moderate side effects

gout; anaemia; increased liver enzymes

Serious side effects

tendon rupture — requires immediate medical attention

Dosage forms

Film-coated tablet

Administration route

Oral use

Patient summary

Utilized to target hypercholesterolaemia to mitigate cardiovascular risk.

Prescription status

POM

Manufacturer

Daiichi Sankyo

Onset Time

2–4 weeks

Duration

Ongoing

Storage instructions

Store below 30°C.

Drug interactions

Simvastatin; Pravastatin

Age restrictions

Not for use in children.

Pregnancy and breastfeeding

Pregnancy: Contraindicated. Breastfeeding: Do not use during breastfeeding.

Precautions and warnings

monitor uric acid levels; caution in patients with history of gout; monitor for tendon rupture

Mechanism of action

Bempedoic acid inhibits ATP-citrate lyase, an enzyme involved in cholesterol biosynthesis in the liver, resulting in reduced LDL-cholesterol levels in the blood.

Nexletol

Utilized to target hypercholesterolaemia to mitigate cardiovascular risk.

Editorial Notes

  • Active ingredient(s): Bempedoic Acid
  • Listed indication(s): Primary Hypercholesterolaemia, Mixed Dyslipidaemia

Available option

  • 60 tablets - 180 mg1473-180-mg-17698