Hygroton

utilized to mitigate excess fluid retention and intended to support the management of essential hypertension.

Strengths: 6.25 · 12.5mg

Medicine details

Therapeutic class

Thiazide-like Diuretic

Pharmacological class

Thiazide-like Diuretic

Known off-label uses

nephrogenic diabetes insipidus

Contraindications

anuria; severe renal insufficiency; hypersensitivity to sulfonamides

Minor side effects

dizziness; fatigue; muscle cramps

Moderate side effects

hypokalaemia; hyperuricaemia; hyponatraemia

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Sanofi

Onset Time

2 hours

Duration

24–72 hours

Storage instructions

Store at controlled room temperature.

Drug interactions

lithium; nsaids

Precautions and warnings

monitor potassium levels; regular blood sugar checks; caution in patients with gout

Serious side effects

severe electrolyte imbalance — requires immediate medical attention; acute pancreatitis — requires immediate medical attention

Patient summary

utilized to mitigate excess fluid retention and intended to support the management of essential hypertension.

Mechanism of action

Chlorthalidone acts on the distal convoluted tubule in the kidney to inhibit sodium and chloride reabsorption, increasing water excretion and lowering blood pressure while maintaining efficacy over 24 hours.

Pregnancy and breastfeeding

Pregnancy: Monitor closely if used during pregnancy. Breastfeeding: Chlorthalidone passes into breast milk; use with caution.

Hygroton

utilized to mitigate excess fluid retention and intended to support the management of essential hypertension.

Editorial Notes

  • Active ingredient(s): Chlorthalidone
  • Listed indication(s): Hypertension, Oedema

Available option

  • 90 tablets - 12.5 mg1042-12-5-mg-13088