Trandate
This medicine is developed to target hypertension and is utilized to alleviate severe high blood pressure in clinical settings.
Strengths: 50 · 100 · 200mg
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Medicine details
- Conditions
- Therapeutic class
Alpha/Beta-blocker
- Pharmacological class
Non-selective beta-blocker
- Minor side effects
dizziness; fatigue; tinnitus
- Moderate side effects
nasal congestion; postural hypotension; ejaculatory failure
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Aspen Pharma
- Onset Time
1–2 hours
- Duration
8–12 hours
- Storage instructions
Store below 30°C, in original packaging.
- Drug interactions
verapamil; cimetidine; tricyclic antidepressants
- Age restrictions
Use with caution in elderly patients.
Contraindications
hypersensitivity to labetalol; second- or third-degree heart block; bradycardia; uncontrolled heart failure; cardiogenic shock
Precautions and warnings
monitor blood pressure continuously; do not stop abruptly; caution in asthma patients
Serious side effects
bradycardia — requires immediate medical attention; heart failure — requires immediate medical attention
Patient summary
This medicine is developed to target hypertension and is utilized to alleviate severe high blood pressure in clinical settings.
Mechanism of action
Labetalol acts as a competitive antagonist of both alpha-1 and non-specific beta-adrenergic receptors. This dual activity causes peripheral vasodilation and reduces cardiac output, effectively lowering systemic blood pressure.
Pregnancy and breastfeeding
Pregnancy: Used in pregnancy for hypertension under strict supervision. Breastfeeding: Excreted in breast milk; monitor infant.
Trandate
This medicine is developed to target hypertension and is utilized to alleviate severe high blood pressure in clinical settings.
Editorial Notes
- Active ingredient(s): Labetalol
- Listed indication(s): Hypertension, Hypertensive Emergency
Usually available as
- 90 tablets - 50 mg637-50-mg-1531
- 30 tablets - 100 mg637-100-mg-4389
- 30 tablets - 200 mg637-200-mg-4395