Revatio
Indicated for pulmonary arterial hypertension and developed to alleviate symptoms.
Strengths: 20mg
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Medicine details
- Conditions
- Alternative names
Viagra; Vizarsin; Sildenafil Actavis
- Therapeutic class
Phosphodiesterase-5 Inhibitor
- Pharmacological class
PDE5 Inhibitor
- Minor side effects
headache; flushing; dyspepsia
- Moderate side effects
peripheral oedema; back pain; muscle pain
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 hours
- Duration
Ongoing treatment
- Storage instructions
Store at room temperature, away from moisture.
- Drug interactions
nitrates; alpha-blockers; ritonavir
- Age restrictions
Not for paediatric use unless specifically indicated.
- Pregnancy and breastfeeding
Consult specialist; benefits must outweigh risks.
Contraindications
concurrent use of nitrates; hypersensitivity to sildenafil; severe hepatic impairment
Precautions and warnings
regular blood pressure monitoring recommended; caution in patients with history of cardiovascular events
Serious side effects
visual disturbance — requires immediate medical attention; hypotension — requires immediate medical attention
Patient summary
Indicated for pulmonary arterial hypertension and developed to alleviate symptoms.
Mechanism of action
Sildenafil inhibits the enzyme PDE5, resulting in elevated levels of cyclic guanosine monophosphate in the pulmonary vasculature, which promotes smooth muscle relaxation and vasodilation.
Revatio
Indicated for pulmonary arterial hypertension and developed to alleviate symptoms.
Editorial Notes
- Active ingredient(s): Sildenafil
- Listed indication(s): Pulmonary Arterial Hypertension
Available option
- 60 tablets - 20 mg378-20-mg-4068