Ranexa

Product indicated to support angina pectoris management and designed to relieve symptoms by modifying cardiac ionic currents.

Strengths: 500 · 1000mg

Medicine details

Therapeutic class

Anti-anginal Drug

Pharmacological class

Late Sodium Current Inhibitor

Minor side effects

dizziness; constipation; nausea; headache

Moderate side effects

fatigue; asthenia; blurred vision

Dosage forms

Prolonged-release tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Menarini

Onset Time

1–2 days

Duration

24 hours

Drug interactions

ketoconazole; verapamil; diltiazem; simvastatin

Age restrictions

Not recommended for those under 18 years.

Pregnancy and breastfeeding

Pregnancy: Not recommended. Breastfeeding: Not recommended.

Contraindications

hypersensitivity; severe renal impairment; severe hepatic impairment; concurrent use of potent CYP3A4 inhibitors

Precautions and warnings

monitor for arrhythmias; use caution in elderly patients; regular electrocardiogram monitoring required

Serious side effects

qt prolongation — requires immediate medical attention; ventricular arrhythmias — requires immediate medical attention; syncope — requires immediate medical attention

Patient summary

Product indicated to support angina pectoris management and designed to relieve symptoms by modifying cardiac ionic currents.

Mechanism of action

This medicine inhibits the late sodium current in heart muscle cells, which prevents sodium and calcium overload, improving cardiac relaxation and blood flow efficiency.

Storage instructions

Store at room temperature, keep in original packaging, and protect from moisture.

Ranexa

Product indicated to support angina pectoris management and designed to relieve symptoms by modifying cardiac ionic currents.

Editorial Notes

  • Active ingredient(s): Ranolazine
  • Listed indication(s): Stable Angina Pectoris

Usually available as

  • 60 tablets - 500 mg1060-500-mg-15568
  • 30 tablets - 1000 mg1060-1000-mg-15572