Premarin®

Indicated to manage menopausal symptoms, formulated to alleviate hormonal fluctuations and support bone and systemic health in postmenopausal women.

Strengths: 0.625mg

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Medicine details

Alternative names

Premique

Therapeutic class

Oestrogen

Pharmacological class

Oestrogen

Known off-label uses

osteoporosis prevention

Minor side effects

nausea; breast tenderness

Moderate side effects

fluid retention; abdominal cramps; mood changes

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

days to weeks

Duration

long term

Storage instructions

Store below 25°C.

Drug interactions

carbamazepine; phenobarbital

Age restrictions

Postmenopausal women.

Pregnancy and breastfeeding

Not applicable.

Contraindications

known or suspected breast cancer; unexplained vaginal bleeding; thrombosis; liver disease

Precautions and warnings

regular breast examinations recommended; monitor for signs of venous thromboembolism

Serious side effects

venous thromboembolism — requires immediate medical attention; endometrial cancer — requires immediate medical attention

Patient summary

Indicated to manage menopausal symptoms, formulated to alleviate hormonal fluctuations and support bone and systemic health in postmenopausal women.

Mechanism of action

Premarin provides a mixture of conjugated oestrogens, which replace the oestrogen that the body no longer produces in sufficient quantities after menopause. This helps to alleviate vasomotor symptoms such as hot flushes and night sweats while maintaining bone density.

Premarin®

Indicated to manage menopausal symptoms, formulated to alleviate hormonal fluctuations and support bone and systemic health in postmenopausal women.

Editorial Notes

  • Active ingredient(s): Conjugated Oestrogens
  • Listed indication(s): Menopausal Symptoms

Available option

  • 28 tablets - 0.625 mg987-0-625-mg-12363