Mestinon

Formulated to address muscle weakness, utilized to support neuromuscular transmission and to relieve fatigue in myasthenia gravis.

Strengths: 60mg

Medicine details

Therapeutic class

Acetylcholinesterase Inhibitor

Pharmacological class

Parasympathomimetic

Contraindications

mechanical intestinal obstruction; urinary tract obstruction; hypersensitivity

Minor side effects

nausea; abdominal cramps; diarrhoea

Moderate side effects

bradycardia; bronchial secretions; muscle fasciculations

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Meda

Onset Time

30–60 minutes

Duration

4–6 hours

Storage instructions

Store at room temperature in a dry place.

Drug interactions

beta-blockers; aminoglycosides

Age restrictions

Suitable for children and adults under specialist guidance.

Precautions and warnings

caution in patients with asthma; monitor for cholinergic crisis; use with care in patients with bradycardia

Serious side effects

cholinergic crisis — requires immediate medical attention; convulsions — requires immediate medical attention

Patient summary

Formulated to address muscle weakness, utilized to support neuromuscular transmission and to relieve fatigue in myasthenia gravis.

Mechanism of action

Pyridostigmine inhibits the enzyme acetylcholinesterase, which breaks down acetylcholine at the neuromuscular junction, thereby increasing the availability of acetylcholine to stimulate muscle contraction.

Pregnancy and breastfeeding

Pregnancy: Use only when strictly necessary. Breastfeeding: Small amounts excreted; monitor infant.

Mestinon

Formulated to address muscle weakness, utilized to support neuromuscular transmission and to relieve fatigue in myasthenia gravis.

Editorial Notes

  • Active ingredient(s): Pyridostigmine
  • Listed indication(s): Myasthenia Gravis

Available option

  • 60 tablets - 60 mg573-60-mg-1280