Imitrex

Developed to alleviate migraine symptoms and intended to support patient comfort.

Strengths: 25 · 50 · 100mg

Medicine details

Alternative names

Imigran

Therapeutic class

5-HT1 Receptor Agonist

Pharmacological class

Triptan

Precautions and warnings

use with caution in patients with history of seizures; may cause drowsiness

Minor side effects

nausea; dizziness; fatigue

Moderate side effects

tingling; hot flush; chest tightness

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

GSK

Onset Time

30–60 minutes

Duration

4–6 hours

Storage instructions

Store below 30°C, away from light.

Drug interactions

ergotamine; MAO inhibitors; SSRIs

Age restrictions

Not recommended for children.

Pregnancy and breastfeeding

Use only if necessary and under medical supervision.

Contraindications

history of myocardial infarction; uncontrolled hypertension; concurrent use of ergotamine derivatives

Serious side effects

arrhythmia — requires immediate medical attention; angina pectoris — requires immediate medical attention

Patient summary

Developed to alleviate migraine symptoms and intended to support patient comfort.

Mechanism of action

Sumatriptan acts as a selective 5-HT1 receptor agonist, causing vasoconstriction of intracranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides.

Imitrex

Developed to alleviate migraine symptoms and intended to support patient comfort.

Editorial Notes

  • Active ingredient(s): Sumatriptan
  • Listed indication(s): Migraine, Cluster Headache

Usually available as

  • 30 tablets - 25 mg373-25-mg-3189
  • 10 tablets - 50 mg373-50-mg-3193
  • 10 tablets - 100 mg373-100-mg-1175