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Medicine details

Conditions: Overactive Bladder
Alternative names: Detrusitol XL
Therapeutic class: Muscarinic antagonist
Pharmacological class: Antimuscarinic
Minor side effects: dry mouth; headache; dry eyes
Moderate side effects: constipation; dyspepsia; blurred vision
Dosage forms: Prolonged-release capsule, hard
Administration route: Oral use
Patient summary: Designed to alleviate symptoms of urinary urgency and frequency.
Prescription status: POM
Manufacturer: Pfizer
Onset Time: 1–2 hours
Duration: 24 hours
Storage instructions: Store at room temperature in a dry place.
Drug interactions: ketoconazole; other anticholinergics
Age restrictions: Not recommended for children.
Pregnancy and breastfeeding: Pregnancy: Not recommended. Breastfeeding: Not recommended.

Contraindications

urinary retention; uncontrolled angle-closure glaucoma; severe ulcerative colitis

Precautions and warnings

caution in patients with obstructive gastrointestinal diseases; monitor for urinary retention; can cause dry mouth

Serious side effects

urinary retention — requires immediate medical attention; angioedema — requires immediate medical attention

Mechanism of action

It serves as a competitive antagonist of muscarinic receptors, which inhibits bladder contraction to increase bladder capacity.

Designed to alleviate symptoms of urinary urgency and frequency.