Combipres
utilized to alleviate high blood pressure by stimulating central alpha-2 receptors.
Strengths: 0.1/15g/mg
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Medicine details
- Conditions
- Alternative names
Catapres
- Therapeutic class
Antihypertensive
- Pharmacological class
Alpha-2 Adrenergic Agonist
- Contraindications
severe heart block; hypersensitivity to components
- Precautions and warnings
do not discontinue treatment abruptly; use with care in renal failure
- Minor side effects
dry mouth; sedation; dizziness
- Moderate side effects
constipation; fatigue; bradycardia
- Serious side effects
severe rebound hypertension — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Boehringer Ingelheim
- Onset Time
30–60 minutes
- Duration
6–10 hours
- Storage instructions
Store in a cool, dry place.
- Drug interactions
alcohol; beta blockers; sedatives
- Age restrictions
Not for paediatric use.
- Pregnancy and breastfeeding
Pregnancy: Use only when clearly necessary. Breastfeeding: Seek medical advice.
Patient summary
utilized to alleviate high blood pressure by stimulating central alpha-2 receptors.
Mechanism of action
Combipres stimulates alpha-2 adrenergic receptors in the brain stem. This activation reduces sympathetic outflow from the central nervous system, resulting in lowered peripheral vascular resistance and lowered heart rate, which effectively decreases blood pressure levels.
Combipres
utilized to alleviate high blood pressure by stimulating central alpha-2 receptors.
Editorial Notes
- Active ingredient(s): Clonidine
- Listed indication(s): Hypertension
Available option
- 200 tablets - 0.1/15 g/mg671-0-1-15-g-mg-2509