Zestril
Designed to relieve hypertension and indicated to support cardiovascular health in patients.
Strengths: 2.5 · 5 · 10mg
Where to Check Availability
Medicine details
- Alternative names
Lopace; Prinivil
- Therapeutic class
ACE Inhibitor
- Pharmacological class
ACE Inhibitor
- Known off-label uses
diabetic nephropathy
- Contraindications
history of angioedema; pregnancy; renal artery stenosis
- Minor side effects
dizziness; headache; fatigue; dry cough
- Moderate side effects
hypotension; diarrhoea; rash; nausea
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
AstraZeneca
- Onset Time
1 hour
- Duration
24 hours
- Storage instructions
Store below 25°C.
- Drug interactions
Potassium-sparing diuretics; Potassium supplements; NSAIDs
- Age restrictions
Use with caution in children over six years.
- Pregnancy and breastfeeding
Pregnancy: Discontinue immediately. Breastfeeding: Not recommended.
Precautions and warnings
monitor renal function; check blood pressure regularly; may cause lightheadedness on standing
Serious side effects
angioedema — requires immediate medical attention; hyperkalaemia — requires immediate medical attention; jaundice — requires immediate medical attention
Patient summary
Designed to relieve hypertension and indicated to support cardiovascular health in patients.
Mechanism of action
This agent inhibits the angiotensin-converting enzyme, which prevents the conversion of angiotensin I to the potent vasoconstrictor angiotensin II. This leads to widened blood vessels, reduced workload on the heart, and lower systemic blood pressure.
Zestril
Designed to relieve hypertension and indicated to support cardiovascular health in patients.
Editorial Notes
- Active ingredient(s): Lisinopril
- Listed indication(s): Hypertension, Heart Failure, Myocardial Infarction
Usually available as
- 360 tablets - 2.5 mg70-2-5-mg-4608
- 180 tablets - 5 mg70-5-mg-4613
- 120 tablets - 10 mg70-10-mg-4619