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Medicine details

Conditions: Plaque Psoriasis
Therapeutic class: Corticosteroid; Vitamin D analogue
Pharmacological class: Glucocorticoids; Vitamin D3 derivative
Minor side effects: pruritus; skin irritation
Moderate side effects: folliculitis; skin atrophy; pigmentary changes
Dosage forms: Cream
Administration route: Cutaneous use
Patient summary: intended to target inflammatory skin lesions to alleviate psoriasis symptoms.
Prescription status: POM
Manufacturer: LEO Pharma
Onset Time: 1–2 weeks
Duration: up to 8 weeks
Storage instructions: Store below 25°C.
Age restrictions: Not for children under 18 years.

Contraindications

calcium metabolism disturbance; viral skin infections; tuberculosis of the skin; hypersensitivity to components

Precautions and warnings

avoid application on the face; limit total weekly dosage; avoid excessive exposure to sunlight

Serious side effects

hypercalcaemia — requires immediate medical attention; cushing's syndrome — requires immediate medical attention

Mechanism of action

Combines a potent corticosteroid for anti-inflammatory effects and a vitamin D analogue to regulate skin cell growth and reduce hyperproliferation.

Pregnancy and breastfeeding

Pregnancy: Use with caution only if benefits outweigh risks. Breastfeeding: Avoid application to the breasts.

intended to target inflammatory skin lesions to alleviate psoriasis symptoms.