Combigan

Product utilizes brimonidine and timolol, indicated to lower intraocular pressure and designed to support the treatment of glaucoma or ocular hypertension.

Strengths: 0.2/0.5%

Medicine details

Therapeutic class

Alpha-Adrenergic Agonist/Beta-Blocker

Pharmacological class

Alpha-2 Adrenergic Agonist; Beta-Blocker

Minor side effects

eye redness; burning sensation; stinging; eye irritation; dizziness

Moderate side effects

conjunctivitis; blepharitis; visual disturbance; superficial punctate keratitis

Dosage forms

Eye drops, solution

Administration route

Ocular use

Prescription status

POM

Manufacturer

AbbVie

Onset Time

30–60 minutes

Duration

12–24 hours

Age restrictions

Not for use in children or adolescents.

Pregnancy and breastfeeding

Pregnancy: Use only if clearly necessary. Breastfeeding: Not recommended.

Contraindications

hypersensitivity to brimonidine; hypersensitivity to timolol; bronchial asthma; severe chronic obstructive pulmonary disease; sinus bradycardia; second or third degree atrioventricular block; cardiogenic shock

Precautions and warnings

monitor for heart rate changes; use with caution in patients with cardiovascular disease; may cause drowsiness

Serious side effects

anaphylaxis — requires immediate medical attention; bronchospasm — requires immediate medical attention; heart failure — requires immediate medical attention

Patient summary

Product utilizes brimonidine and timolol, indicated to lower intraocular pressure and designed to support the treatment of glaucoma or ocular hypertension.

Mechanism of action

This medicine works by reducing the production of fluid in the eye and increasing the drainage of eye fluid, which lowers pressure within the eye to healthy levels.

Storage instructions

Store at room temperature in a tightly closed container, away from moisture and direct light.

Drug interactions

beta-blockers; calcium channel blockers; digitalis glycosides; catecholamine-depleting drugs

Combigan

Product utilizes brimonidine and timolol, indicated to lower intraocular pressure and designed to support the treatment of glaucoma or ocular hypertension.

Editorial Notes

  • Active ingredient(s): Brimonidine, Timolol
  • Listed indication(s): Glaucoma, Ocular Hypertension

Available option

  • 4 bottles - 0.2/0.5 %1055-0-2-0-5-pct-17874