Ciprodex

indicated to manage bacterial ear infections and formulated to alleviate inflammation and oedema within the ear canal.

Strengths: 0.3/0.1%

Medicine details

Alternative names

Cilodex; Ciprofloxacin + Dexamethasone Ear Drops

Therapeutic class

Corticosteroid and Antiinfective

Pharmacological class

Fluoroquinolone / Corticosteroid

Minor side effects

application site pruritus; ear discomfort

Moderate side effects

ear congestion; taste perversion

Dosage forms

Ear drops, solution

Administration route

Ocular use

Prescription status

POM

Manufacturer

Novartis

Onset Time

1–2 days

Duration

7–10 days

Storage instructions

Store below 25°C. Do not freeze.

Age restrictions

Not recommended for children under 6 months.

Contraindications

hypersensitivity to fluoroquinolones; viral infections of the ear canal; fungal infections of the ear canal; tuberculous infections of the ear

Precautions and warnings

discontinue at first sign of skin rash; prolonged use may result in overgrowth of non-susceptible organisms

Serious side effects

anaphylaxis — requires immediate medical attention; hypersensitivity reaction — requires immediate medical attention

Patient summary

indicated to manage bacterial ear infections and formulated to alleviate inflammation and oedema within the ear canal.

Mechanism of action

This product combines a fluoroquinolone antibiotic, which inhibits bacterial DNA gyrase and topoisomerase IV, with a potent corticosteroid that suppresses the inflammatory response by inducing phospholipase A2 inhibitory proteins.

Pregnancy and breastfeeding

Pregnancy: Use only if the potential benefit outweighs the risk to the foetus. Breastfeeding: Use with caution; systemic absorption is minimal.

Ciprodex

indicated to manage bacterial ear infections and formulated to alleviate inflammation and oedema within the ear canal.

Editorial Notes

  • Active ingredient(s): Ciprofloxacin, Dexamethasone
  • Listed indication(s): Acute Otitis Externa, Acute Otitis Media in Patients with Tympanostomy Tubes